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New method reveals how well TB antibiotics reach their targets
Scientists have developed a new technique that enables them to visualise how well antibiotics against tuberculosis (TB) reach their pathogenic targets inside human hosts. The findings, published in the journal Science, boost our understanding of how antibiotics work and could help guide the development of new antibiotics, which are much-needed in the battle against drug-resistance.
Men’s Health in South Africa
The purpose of Men’s Health Month is to heighten the awareness of preventable health problems and encourage early detection and treatment of disease among men and boys. This month gives health care providers, public policy makers, the media, and individuals an opportunity to encourage men and boys to seek regular medical advice and early treatment for disease and injury. 
NIH launches large TB prevention trial for people exposed to multidrug-resistant TB
A large clinical trial to assess treatments for preventing people at high risk from developing multidrug-resistant tuberculosis (MDR-TB) has begun. The study is comparing the safety and efficacy of a new MDR-TB drug, delamanid, with the decades-old TB drug isoniazid for preventing active MDR-TB disease in children, adolescents and adults at high risk who are exposed to adult household members with MDR-TB.
USAID Tuberculosis South Africa Project has 11 abstracts accepted to the 50th UNION Lung Conference
USAID Tuberculosis South Africa Project staff will present 11 abstracts at the prestigious 50th UNION Lung Conference, which is scheduled to be held in Hyderabad, India, from October 30th to November 2nd, 2019.
USAID Tuberculosis South Africa Project hosts one of a few TB-themed sessions at the recent 9th South Africa AIDS Conference
Despite tuberculosis (TB) and HIV assuming twin epidemic status in South Africa and other sub-Saharan African countries, TB continues to be underrepresented in HIV research spaces. It was evident at the recent 9th South Africa AIDS Conference (SAAIDS), where presentations about TB were uncommon.
A battle with TB inspired his smart medicine dispenser, now it’s won Africa’s top engineering prize
After being diagnosed with tuberculosis in January 2014, Neo Hutiri needed medicines monthly in order to treat it. Every visit meant spending up to three and a half hours in a queue waiting for his turn at the hospital pharmacy in Johannesburg. “Most of the other patients that waited along with me had to miss work just to collect their medicine,” he says.
Stellenbosch University study aims to ‘protect’ anti-TB drug
Scientists at Stellenbosch University (SU), in collaboration with a multidisciplinary team of researchers and clinicians, are working to conserve a drug that improves the survival of patients with multidrug-resistant TB – by studying how Mycobacterium tuberculosis, the bacterium that causes TB, can develop resistance.
TB LAM test improves TB diagnosis in people with low CD4 counts
Use of the TB LAM test in people with HIV with CD4 counts below 200 boosted the number of people diagnosed with tuberculosis (TB) by a third, an observational study in Malawi and Mozambique has found. Almost half of TB cases would have been missed if LAM had not been included in the diagnostic algorithm, showing that the test is useful in a far wider population than currently recommended.
The Union highlights child TB on the International Day of Families
An estimated 239,000 children die every year from TB. Most of these deaths are preventable. TB is both treatable and curable, but 90 percent of children who die from TB did not receive the standard treatment that could have saved their lives.
Drug-resistant tuberculosis reversed in lab
About 1.5 million people died of tuberculosis (TB) in 2017, making it the most lethal infectious disease worldwide. A growing rise in drug-resistant TB is a major obstacle to successfully treating the illness. Now, researchers at Washington University School of Medicine in St. Louis and Umea University in Sweden have found a compound that prevents and even reverses resistance to isoniazid, the most widely used antibiotic for treating tuberculosis.

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